Talislanta is such a rich, interesting world. But as I was reviewing 4th edition I kept thinking what a herculean effort it would be to consume this all at once. If I were to run a Talislanta campaign I think I would want to start in one nation and slowly move across the world, allowing players to explore a limited number of archetypes from that region before moving to a different region and trying out their archetypes. Trying to imagine what sort of framework would support that type of play. It wouldn't have to be an epic story line - could just be a group of wandering rogues that hit little 'micro-dungeons' in each land, lose some people and take on new party members from the local culture.